An issue of the newsletter will be published once every three months. Every four issues published per calendar year will comprise one Volume.

Volume 3, Issue 2

Horizon 2020 European PI Project

David Reay and Associates (DRA – see is one of 22 partners across Europe in an HORIZON 2020 (H2020) project in the area of Process Intensification (PI), funded by the European Commission to the tune of approximately €10 million. The project – called Intensified-by-Design® (IbD®) is led by IRIS. IRIS is an advanced engineering company that specializes in process monitoring and control solutions and novel technologies for process optimization (an area highly relevant to the IbD project), with headquarters in Barcelona and facilities in Dublin. DRA plays a fundamental role in several of the work packages, which include the supervision of the chemical process design methodology and management of the Process Intensification Implementation Team (PIIT), as well as coordinating the cohesion of all PI case studies. DRA is utilising tools – state-of-the-art review, ‘expert system analysis’, and numerical simulations, among others – to contribute towards the success of this project……… Click HERE to read more.

Volume 3, Issue 1

Process Intensification: Research and Industrial Applications in China

Process intensification (PI) involves at least one of the intensification elements of mass transfer, momentum transfer, heat transfer, and reaction rate/selectivity/productivity. As the main direction of chemical industry, it has been attracting more and more academic and industrial interest. PI in China has met great opportunity due to the important issues on energy saving and waste reducing appeared in the national plan. In this review, PI researches and industrial applications in China are summarized; PI is classified as four general types (miniaturization, external field intensification, special medium/solvent intensification, and coupling intensification) with corresponding applications in three major areas (separation, reaction, and heat transfer). The review points out that PI needs more engineering and engineering-trained researchers for industrial implementations…….. Click HERE to read more.

Volume 2, Issue 4

PI & S: Subcritical Water as an Alternative Solvent for Particle Engineering Process

Water is used in many reaction and separation processes due to more chemical industries shifting towards sustainability. The strong hydrogen-bond cohesive energy between the water molecules causes low solubility of hydrophobic compounds in water. However, the hydrogen-bond in water weakens when the temperature increases, which leads to the solvating power of water for hydrophobic compounds increasing. Hence, water at temperatures above the ambient boiling temperature can be used for materials extraction, such as ionic and polar species extraction at modest temperature and non-polar materials extraction at higher temperature (near critical condition). Besides extraction, pressurised water at high temperature can also be used in hydrolysis reactions by hydrothermal transformations to obtain fuel from non-food plant material……. Click HERE to read more.

Volume 2, Issue 3

Electroless Metal Plating – A New Era

A new generation of electroless copper plating solution process that can reduce plating time by more than 100% has been developed. Based on fundamental solution chemistry and focusing on limiting the side reactions involved in an electroless copper plating process, it is possible to overcome the current formulation dilemma of using high doses of stabilizing agent to ensure plating stability which sacrifices plating speed…… Click HERE to read more.

Volume 2, Issue 2

ARISE – A Novel Micronization Process

Particle engineering of inhalable pharmaceuticals is increasingly attracting the attention of researchers. There are several conventional micronization techniques for production of micron-sized particles that are available such as mechanical milling and grinding, spray drying and freeze drying. High-pressure processes using supercritical fluid (SCF) for particle micronization present distinct advantages over the conventional methods. The unique tuneable properties of SCFs have offered the ability to control particle formation and characteristics…… Click HERE to read more.

Volume 2, Issue 1

Controlled Release Nano-Carriers Marching towards Process Intensification

Targeted drug delivery has been popular in pharmaceutical research for decades. Its great benefits include drug dosage control, drug release rate, improvement of therapeutic efficacy and minimisation of side effects of drugs. Nano-carriers such as liposomes, polymersomes and micelles find useful application in targeted delivery. They carry Active Pharmaceutical Ingredients (APIs) in the human body. As the carriers have long circulation times in the body, they are able to reach the targeted sites because their outer membrane is similar to human body cells.

Why Dense Gas Technology?…… Click HERE to read more.

Volume 1, Issue 1

Process Intensification – High Gravity Reaction Technology (Higee Technology)

Process intensification (PI) is an innovation on process and equipment that results in more efficient of process unit operations and often a dramatic reduction of equipment size. The advantages of PI may include improvement of product quality, energy saving, reduction of operation cost, reduction of resource consumption, minimisation of pollution, and improvement of safety.

High Gravity Reaction Technology (Higee technology) is a practical example of PI that has been commercialised…… Click HERE to read more.

See – Special Issue: High Gravity Technology – a Personal Perspective by S.L.Jimmy Yun